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About & Wisdom

Old knowledge, carefully kept.

Where Ayurveda comes from, who checks our work, and what modern research does and does not yet show.

01 · Lineage & philosophy

Fifteen centuries in five eras

Broad, overlapping periods marking how the knowledge was kept, taught and regulated.

c. 700–1500 CE

Materia medica

Nighantus catalogues · Rasashastra traditions · Powders, decoctions, oils, pastes

Some mineral and metal preparations can carry hazardous amounts of lead, mercury or arsenic.

1500–1947

Lineage and region

Practitioner lineages · Manuscripts and printed books · Local dispensaries · Household remedies

Practice and materials differed by region and by lineage.

1947–2000

Institutions

College curricula · Hospitals · Pharmacopoeial work · Regulated manufacturing

Standardisation does not automatically establish clinical effectiveness.

2000–2014

Research infrastructure

Medicinal-plant programmes · Research databases · Department of AYUSH, 2003

Findings differ by treatment and by study quality.

2014–2026

Contemporary standards

Ministry of AYUSH, 2014 · WHO benchmarks, 2022 · International terminology, 2023 · Pharmacovigilance

Clinical decisions should consider evidence, contraindications, interactions and patient safety.

02 · Practitioners

Who reviews our work

Named profiles will be published as the advisory board is confirmed.

BAMS · Clinical review

Ayurvedic physicians

Review every protocol, therapy description and seasonal guide for classical accuracy and safety.

Pharmacology

Clinical pharmacologists

Check herb-drug interactions and contraindications before anything is published.

Genomics & data

Research scientists

Grade each claim by evidence tier and keep source links current.

03 · The science

Prakriti in the genome

Five molecular correlates studied so far. Promising, but still early.

Phase‑I drug‑metabolizing enzyme

CYP2C19

A liver enzyme that clears roughly a tenth of common prescription drugs. In a 132‑person genotyping study, 91% of Pitta‑Prakriti individuals carried fast‑metabolizer genotypes, while poor‑metabolizer genotypes were 2.5–3.4× more frequent in Kapha, lining up with the classical claim that Pitta runs a "fast" metabolism and Kapha a "slow" one.

rs11208257 · c.1258T>C (p.Tyr420His)

PGM1

A gene sitting at the crossroads of five energy‑metabolism pathways: glycolysis, gluconeogenesis, galactose and starch/sucrose metabolism. In a genome‑wide scan this variant tracked specifically with Pitta, the type classical texts describe as having the sharpest digestive fire (Agni) and fastest energy turnover.

rs479200 / rs480902 · HIF pathway

EGLN1

An oxygen-sensing gene that controls how the body responds to low‑oxygen environments. The high‑expression variant was more common in Kapha types and tracked with high‑altitude pulmonary edema risk, while Pitta types, and populations native to high altitude, carried it far less often.

Immunophenotype markers

CD25 / CD56

Flow‑cytometry markers for activated B‑cells (CD25) and natural killer cells (CD56). Kapha‑Prakriti individuals showed significantly elevated levels of both, a candidate molecular basis for the classical description of Kapha as the most immunologically resilient constitution.

0 Prakriti-stratified human RCTs published to date. Associations above do not yet prove that matching treatment to Prakriti improves outcomes.

Evidence and sources Our 8-step method
04 · FAQ

Common questions

Is the Prakriti quiz a diagnosis?

No. It is an educational demo based on published questionnaires. A full assessment needs a qualified practitioner.

Can I take herbs with my prescriptions?

Not without checking first. Piperine, for example, changes how many drugs are absorbed. Speak to your doctor or a BAMS practitioner.

How strong is the evidence for Prakriti?

Early. Some genetic associations exist, but 0 Prakriti-stratified human RCTs have been published to date.

Do you sell mineral or metal preparations?

No. Some have been found to contain hazardous levels of lead, mercury or arsenic.

Is Panchakarma safe to do at home?

No. It should only be done under qualified medical supervision.